For instance, if you are taking medications for diabetes and your blood sugar remains normal, there is a good . Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Also used in the treatment of chronic stable angina in patients intolerant of, or not adequately controlled by, beta-blockers or nitrates. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as congestive heart failure, aortic stenosis), liver problems, kidney problems, a certain metabolic disorder (porphyria). Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Headache, dizziness, nausea, flushing, constipation, leg/muscle cramps, or sexual problems may occur. The dosage of nifedipine must be established by slow titration as excessive dosages can result in hypotension, preferably over a 7 to 14 day period. How quickly can acute migraines be treated. Properly discard this product when it is expired or no longer needed. However, Dr. Ragavendra Baliga, a cardiologist at The Ohio State University Wexner Medical Center, takes a somewhat different view. Store drug capsules at room temperature between 59F (15C) and 77F (25C). This means you may need to take it with other medications. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Portions of this document last updated: Feb. 01, 2023. Dr. Kim Williams, the head of the division of cardiology at Rush University Medical Center and past president of the American College of Cardiology, says he feels its too soon to begin recommending that all patients take their medications at bedtime. The capsules are available as the brand-name drug. Recursively sort the rest of the list, then insert the one left-over item where it belongs in the list, like adding a card to the hand you've already sorted in a card game, or putting a book away in a sorted bookshelf. Do not stop taking nifedipine suddenly. Nifedipine should not be used to rapidly drop blood pressure as this may be fatal and it should not be taken with grapefruit juice or grapefruit products. You may need to show airport staff the pharmacy label for your medication. About 77% of American women and 68% of men report taking supplements, according to the Council for Responsible Nutrition. For people with low blood pressure: If you have episodes of low blood pressure, taking nifedipine may make these episodes worse. Do not take nifedipine with any grapefruit juice or other products made using grapefruit (such as marmalade). Cardinal Health. Statins & grapefruitor maybe not. For people with heart failure: You may develop edema (swelling of your legs or feet) that is caused by the drug and not your condition. other information we have about you. Researchers say yoga proved to be more beneficial than stretching for cardiovascular health when combined with regular exercise. Nifedipine can pass into breast milk and may harm a nursing baby. Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. Dizziness, light-headedness, flushing, headache, weakness, nausea, heartburn, and muscle cramps or tremor. prevention of anginal chest pain associated with coronary artery disease, prevention of anginal pain associated with vasospastic angina, Raynaud's phenomenon, a condition where blood vessels constrict too much with coldness or stress, pre-existing hypertension during pregnancy. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. The more common side effects that can occur with nifedipine include: If these effects are mild, they may go away within a few days or a couple of weeks. In my opinion this is particularly true in those patients with high BMI (and consequently more likely to have obstructive sleep apnea), elderly (since they have more insomnia), diabetics, and those with chronic kidney disease, Baliga added. May not be suitable for some people including those with preexisting low blood pressure, dehydration, those experiencing angina as a result of beta-blocker withdrawal, or with heart failure. swelling in your hands or lower legs; or. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. allergic reaction (rash; hives; swelling of the face, lips, tongue, or throat; difficulty breathing) signs of bleeding in the stomach (e.g., bloody, black, or tarry stools; spitting up of blood; vomiting blood or material that looks like coffee grounds) Some people may experience side effects other than those listed. Get medical help right away if you experience: worsening chest pain, symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating). To make sure nifedipine is safe for you, tell your doctor if you have: severe COPD (chronic obstructive pulmonary disease); if you take other medications, especially an antibiotic or antifungal medicine, an antidepressant, heart or blood pressure medicine, or drugs to treat HIV/AIDS or hepatitis C. It is not known whether nifedipine will harm an unborn baby. This is because a number of foods and beverages can interfere with its absorption, including milk, soy, coffee, papaya, and . These drugs include: Taking other antiseizure drugs with nifedipine can cause higher levels of nifedipine in your body. This site complies with the HONcode standard for trustworthy health information: verify here. Call your doctor if you become pregnant while taking this drug. This can make it less effective. A class of drugs is a group of medications that work in a similar way. Do not crush or chew the tablets. a light-headed feeling, like you might pass out; pounding heartbeats or fluttering in your chest; chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling; upper stomach pain, jaundice (yellowing of the skin or eyes). Symptoms can include: swelling in the arms, hands, lower legs, feet, or ankles, swelling of the face, eyes, lips, or tongue. Nifedipine works by causing some of your blood vessels to relax and widen. If you're bothered by side effects, you may need to stay on a lower dose. It is primarily used as an antihypertensive and as an anti-anginal medication. information and will only use or disclose that information as set forth in our notice of US residents can call their local poison control center at 1-800-222-1222. Symptoms can include: If you have these symptoms, call 911 or go to the nearest emergency room. Some tablet forms of nifedipine are made with a shell that is not absorbed or melted in the body. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Its also used to treat two types of angina (chest pain): vasospastic angina and chronic stable angina. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use nifedipine only for the indication prescribed. Drug interactions may change how your medications work or increase your risk for serious side effects. This medication is used alone or in combination with other drugs to treat high blood pressure (hypertension). Do not take nifedipine with any grapefruit juice or other products made using grapefruit (such as marmalade). Nifedipine may also be used for purposes not listed in this medication guide. The medicine will come with a plastic syringe or spoon to help you take the right amount. information highlighted below and resubmit the form. That includes 81% of people ages 55 and older. Nifedipine is used to treat hypertension (high blood pressure). Procardia, Procardia XL, Adalat, Nifedical XL, +3 more. information highlighted below and resubmit the form. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Bloating or swelling of the face, arms, hands, lower legs, or feet, fast, irregular, pounding, or racing heartbeat or pulse, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, coughing that sometimes produces a pink frothy sputum, difficult, fast, or noisy breathing, sometimes with wheezing, pain or discomfort in the arms, jaw, back, or neck, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased urge to urinate during the night, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, sores, ulcers, or white spots on the lips or in the mouth, unsteadiness, trembling, or other problems with muscle control or coordination, vomiting of blood or material that looks like coffee grounds, redness of the face, neck, arms, and occasionally, upper chest, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, difficulty having a bowel movement (stool), excess air or gas in stomach or intestines, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, increased sensitivity of the skin to sunlight, itching, pain, redness, swelling, tenderness, or warmth on the skin, redness or other discoloration of the skin, swelling of the breasts or breast soreness in both females and males. In the study, the researchers followed 19,084 patients with high blood pressure for a median of 6 years. If any of these effects last or get worse, tell your doctor or pharmacist promptly. trouble concentrating. Most people with high blood pressure do not feel sick. Exercise regularly (over 150 minutes per week). There have been no controlled studies in humans. Keep taking this medication even if you feel well. For women who are breastfeeding: Nifedipine may pass into breast milk and can cause serious side effects in a child who is breastfed. For people with a history of gastrointestinal blockage: There have been rare reports of gastrointestinal blockage with use of the brand-name drug Procardia XL. They are meant to be absorbed by the body over the course of several hours, so they'll pass through the gastrointestinal tract before they can be fully absorbed. Things to remember when you fill your prescription. Foods containing soy and cottonseed meal can make Synthroid less effective. Qulipta, amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol. Do not take nifedipine if you: are allergic to nifedipine or any of this medication's ingredients; have a specific form of high blood pressure called "essential hypertension." The cause of this type of high blood pressure is unknown. The list of medications is seemingly endless, so it's very . As a result, less pressure is built up and your heart does not have to work as hard to pump blood. DO make sure you eat something and are well hydrated before your appointment, so you feel your best. Canada residents can call a provincial poison control center. Heart disease is responsible for about 325,000 adult deaths in the United States each year and a disproportionate number of them are black women. Generic name: nifedipine [nye-FED-i-peen] Some medicines need to be taken "before food" or "on an empty stomach". Nifedipine is used to treat hypertension (high blood pressure) and angina (chest pain). Nifedipine oral tablet doesnt cause drowsiness. The following article hopes to help you make more suitable choices and get more useful information 5.0 (1 review) Term. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Nifedipine ER oral side effects by likelihood and severity. This makes it less effective. If you are a Mayo Clinic patient, this could Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Advertising revenue supports our not-for-profit mission. Swallow the capsules or tablets whole with a drink of water. Not every pharmacy stocks this drug. These drugs are often used to treat similar conditions. Take the missed dose as soon as you remember. You may have to take high blood pressure medicine for the rest of your life. swelling of the breasts or breast soreness in both females and males. You should not use this medicine if you are allergic to nifedipine, if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. What you eat and drink can cause harmful effects when mixed with certain drugs. Bhusri believes that better compliance may have been the reason that the patients in the study had better blood pressure control. Take this medication by mouth on an empty stomach, usually once daily or as directed by your doctor.Swallow the tablets whole. Uses. If you're not sure, check with your doctor or pharmacist. information is beneficial, we may combine your email and website usage information with Taking these common types of prescriptions and over-the-counter drugs before hitting the gym can negatively affect your exercise performance. Your dose of nifedipine depends on why you need the medicine and what kind your doctor has prescribed. Using these drugs with nifedipine has a low risk of causing heart failure, extremely low blood pressure, or a worsening of chest pain (angina). You may need to use blood pressure medication for the rest of your life. This could make nifedipine less effective. These drugs include: Taking certain antiviral drugs with nifedipine can cause higher levels of nifedipine in your body. Some products have ingredients that could raise your heart rate or blood pressure. It usually does not matter if you take nifedipine with or without food, but check the leaflet of the brand you're taking because the advice can vary. If it is near the time of the next dose, skip the missed dose. Talk with your doctor to find out the true cause of any increased swelling you may have. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. FDA-approved indications include chronic stable angina, hypertension. We need more data from other centers as much of the data favoring this come from a small set of investigators. Many also feel that it is easier to remember morning medications. This is not a complete list of possible side effects. information is beneficial, we may combine your email and website usage information with Speak to your doctor about how drug interactions should be managed. This can increase your risk of side effects from nifedipine. Selected from data included with permission and copyrighted by First Databank, Inc. There are different tablet strengths of this medication available. Runny nose. DOs and DONT's for before, during and after your COVID-19 vaccination. If you miss a dose of this medicine, take it as soon as possible. answer the question why take nifedipine on empty stomach, which will help you get the most accurate answer. If you often forget doses, it may help to set an alarm to remind you. In the US - Call your doctor for medical advice about side effects. Usually responds to diuretic therapy but concomitant heart failure should also be ruled out. You should decide whether you will stop breastfeeding or stop taking nifedipine. Grapefruit juice can increase the amount of certain medications in your bloodstream. Do not crush, chew, or break a nifedipine extended-release tablet. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Nevirapine can cause serious, life-threatening side effects. Always carry the original prescription-labeled box with you. For this drug to work well, a certain amount needs to be in your body at all times. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. If you are using it to treat angina, you may take it with nitrates (nitroglycerin products) or beta-blockers. If you're taking nifedipine as a liquid, shake the bottle well. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. You may need to take an extended-release tablet on an empty stomach. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Do not share this medication with others. Other mouth and throat symptoms sometimes occur, such as gum problems, bad breath, sore throat, hoarseness and a feeling of a lump in the throat. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Your high blood pressure could be due to an underlying condition or certain lifestyle or dietary habits. Some tablet strengths may not be used in place of others. The starting dose is 30 mg or 60 mg by mouth once per day. It will depend on how old your child is and . Do not break, crush, or chew it. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Follow all directions on your prescription label. Follow your doctor's orders or the directions on the label. Available for Android and iOS devices. Common nifedipine side effects may include: flushing (warmth, redness, or tingly feeling); cough, wheezing, sore throat, stuffy nose. Always discuss possible side effects with a healthcare professional who knows your medical history. Common side effects may include: swelling; This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. If you take too much: You could have dangerous levels of the drug in your body. For people with severe heart disease: There have been rare reports of worsening chest pain and heart attack in people who have severe heart disease. If you're bothered by any side effects, your doctor may be able to prescribe you a different medicine. Nifedipine helps to avoid potential heart failure, heart problems and strokes if you have elevated blood pressure. Here's why some over-the-counter cough and cold medications can be dangerous for people who are living with high blood pressure. If you experience any of these symptoms, call your doctor as soon as you can. Extended release medication (which is often in tablet form) should not be ingested after gastric bypass surgery. A very serious allergic reaction to this drug is rare. Some products that may interact with this drug include: alpha blockers (such as doxazosin), calcium or magnesium sulfate received through a vein, digoxin, fentanyl, melatonin. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Liver problems and skin rash and allergic reactions can happen at any time during treatment with nevirapine, but your risk is greatest during the first 18 weeks of treatment. Using doxazosin with nifedipine can lower the amount of doxazosin in your body. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Copyright 1996-2023 Cerner Multum, Inc. The dosage can be increased every 7 to 14 days until the maximum dosage of 90120 mg per day is reached. Nifedipine comes as standard capsules, or more commonly as slow-release tablets or capsules. Low blood pressure or low heart rate. This medication must be taken regularly to be . You may report side effects to FDA at 1-800-FDA-1088. These are all extended-release tablets. This can help keep levels of this drug from building up too much in your body. have gastroinstestinal (stomach and bowel) problems; are pregnant or breastfeeding; Rarely, some patients may experience an increase in the frequency or severity of angina or acute myocardial infarction (heart attack) when starting nifedipine. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates.